Press releases

A team of Czech researchers has achieved a breakthrough in understanding Diamond-Blackfan Anaemia (DBA), a rare and severe genetic disease that cause anemia and inborn malformations in children. By creating a unique mouse model that perfectly mimics the pathologic condition, scientists from the Czech Centre for Phenogenomics (Institute of Molecular Genetics of the Czech Academy of Sciences) and the First Faculty of Medicine, Charles University (BIOCEV) have opened the door to safer, more effective treatments. Their findings were recently published in the prestigious medical journal HemaSphere.

Does contaminated soil pose a public health risk of parasite infection to rural communities in Lao PDR? This is a key question which researchers from the Institute of Vertebrate Biology (IVB) of the Czech Academy of Sciences are helping to address, through collaboration with the French National Research Institute for Sustainable Development (IRD) on the SOLAO (Soil Health Assessment in Laos) Project.

The Masaryk Institute and Archives of the Czech Academy of Sciences has established a strategic cooperarion with the Archives of UNHCR, the UN Refugee Agency. The aim is to jointly process, describe, and make accessible previously inaccessible archival materials relating to the activities of UNHCR in East-Central Europe during the key period of 1994–2004. This project follows on from the ERC grant Unlikely Refuge? led by Michal Frankl. It will enable access to essential sources for understanding refugee policy in post-communist countries.

People, animals and climate change – these are the themes connected by the INVANISH project, which has been awarded a Consolidator Grant by the European Research Council (ERC). Researchers will examine how relationships between humans and animals are changing in everyday life. Their work will focus on four regions of the world where animal movements caused by climate change are particularly visible and where people have had to respond in significant ways.

The signs of oocyte (egg) ageing can be reversed, and damage can be repaired. What was previously considered biologically impossible has been proven by an international research team led by reproductive biologist Helena Fulková from the Institute of Experimental Medicine of the Czech Academy of Sciences. The results, published in the journal Ageing Cell, raise new questions about the biology of ageing and open up space for the development of future therapeutic approaches.

Ideas bold enough to push the limits of human imagination lie at the heart of the Dream Chemistry Award — a joint initiative of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and the Institute of Physical Chemistry of the Polish Academy of Sciences (IChF PAS). Success in this prestigious competition is not measured by publication counts or impact factors; instead, proposals are judged by an international scientific committee for their originality, vision, and potential to redefine the field.

Hana Polášek-Sedláčková from the Institute of Biophysics of the Czech Academy of Sciences is one of 28 young investigators who will be active members of the EMBO Young Investigator Programme for the next four years. Their research projects address a broad range of questions in the life sciences, including topics such as the gut microbiome of infants, the demographics of indigenous American populations, the neural blueprint of brain tumours, and the role of the RNA polymerase II in transcription.

Conspecific brood parasitism – a situation where females lay eggs in the nests of other females of the same species – has long been a mystery to scientists. A team from the Institute of Vertebrate Biology of the Czech Academy of Sciences, in collaboration with colleagues from the UK, has now developed an artificial intelligence model that can recognise parasitic eggs in birds with up to 97% accuracy. The new approach, the results of which were published in the journal Proceedings of the Royal Society B: Biological Sciences, could significantly facilitate and reduce the cost of research into this little-studied phenomenon.

A research team at IOCB Prague led by Jiří Kaleta has described a new concept for light-driven molecular motors that remain fully functional even after being anchored to a metal surface, where they continue to perform controlled rotary motion. The scientists have thus overcome one of the main obstacles on the road to fully controllable molecular machines – a development expected to have a major impact on the creation of intelligent materials, among other applications. The study provides deeper insight into the control of motion at the nanoscale. The paper was published in the journal Angewandte Chemie International Edition.

Overcoming a genetic disorder that leads to serious diseases, and examining the relationship between political party systems and social conflicts in the MENA region — these are the goals of two ERC Synergy Grants awarded to researchers from the Czech Academy of Sciences (CAS). Each grant provides €9.8 million in funding over six years.